Benefits of using plant extracts in fertility preservation with special reference to Moringa oleifera
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Due to the increase in childhood cancer survivors, fertility preservation has become an important issue in the field of cancer management and infertility treatment. However, the limitations of current methods such as semen cryopreservation, testicular tissue cryopreservation, and in vitro spermatogenesis, urges the researchers to explore alternative and practically feasible approaches to protect the gonadal tissue from the cytotoxic chemotherapeutic agents. This review highlights the possible application of natural products, especially the Moringa oleifera leaf extracts in protecting the gonadal tissue from cytotoxic agents, their possible mechanism of action, advantages, current situation and scope for future research.
KEY WORDS: male fertility preservation, gonadal damage, infertility, natural products, plant extract, Moringa oleifera.