Cic edizioni internazionali
Current Trends in Clinical Embryology

Isolated ovarian follicle culture: a promising strategy for fertility preservation

Mini-Review, 177 - 185
doi: 10.11138/cce/2015.2.5.177
Tag this article
Enhanced HTML Full text PDF
Ovarian tissue cryopreservation represents one among the most preferred strategies for fertility preservation currently. However, concerns regarding the transmission of malignant cells during the transplantion of stored ovarian tissues, is a major restraint in recommending the procedure to patients diagnosed with all kinds of malignant disorders.
On the contrary, use of isolated follicles for restoration of fertility in such patients could completely evade the possibility of cancer re-introduction after treatment. Follicles housed in the ovarian environment in vivo prevail under the mechanical and the chemical/nutritional support of the ovary. Although not complete, recent knowledge about the dynamics of follicular progression has led to improvements in the culture system adopted.
This review aims at summarising the culture of isolated follicles in vitro, particularly emphasising the efforts made to mechanically and nutritionally support the follicle. Advances in follicular culture systems could prove useful to highly improve the efficiency of current fertility restoration strategies and evade the concerns associated with the same.

Vol. 5 (No. 3) 2018 September - December

  1. Comparison of ICSI results in a group of patients with and without oral L-carnitine, acetyl-L-carnitine and nutrients supplementation
    Ajina M., Mustapha H., Tagorti S., Virmani M.A.
  2. The role of automation within the ivf laboratory
    Iussig B., Ubaldi F.M., Rienzi L.
  3. The impact of ESHRE basic semen analysis course: 6 years of Italian experience
    Sanchez A.M., Natali I., Costantino A., Pena-Cotarelo R., Terribile M., Rubino P., Castilla J.A., de Mendoza M.V.H.
  4. Fibrin-based artificial ovary prototype: from animal models to human clinical application
    Chiti M.C., Amorim C.A., Dolmans M.M.
  5. Formation and dynamics of the primordial follicle stockpile
    Klinger F.G., Rossi V., Marcozzi S., Sorrenti M., De Felici M.
  6. Human sperm vitrification: state of the art
    Caponecchia L., Coltrinari G., Finocchi F., Sacchetto R., Paoli D.
Last Viewed articles: la lista degli ultimi x visitati.
  1. Isolated ovarian follicle culture: a promising strategy for fertility preservation
    Sudhakaran S., Gualtieri R., Barbato V., Fiorentino I., Braun S., Merolla A., Talevi R.
    doi: 10.11138/cce/2015.2.5.177