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Current Trends in Clinical Embryology

Effects of chemotherapeutic treatment on female reproductive function

Mini-Review, 158 - 166
doi: 10.11138/cce/2015.2.5.158
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As a consequence of the improvement in diagnosis and therapy, many more young women will survive their cancer. For some of them, due to toxic treatments, there is the risk of compromising their reproductive function.
There is a growing body of evidence about the specific effects of different chemotherapy drugs on the ovary, based on in vitro methods, complementing clinical information regarding ovarian function. This information, highlighting the varying effects of these drugs on
the different cells and tissues of the ovary, is reviewed here.

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  1. Effects of chemotherapeutic treatment on female reproductive function
    Lopes F., Spears N., Anderson R.A.
    doi: 10.11138/cce/2015.2.5.158